亚洲国产成人无码AV在线播放,亚洲色偷拍另类无码专区,亚洲AV日韩AV永久无码久久,国产手机在线精品

技術(shù)文章您現(xiàn)在的位置:首頁 > 技術(shù)文章 > BroadPharm-什么是陽離子脂質(zhì)?

BroadPharm-什么是陽離子脂質(zhì)?

更新時間:2022-08-24   點擊次數(shù):1318次

What are Cationic Lipids?

Cationic lipids are a class of lipid molecules with a permanent positive charged head group with structure as exemplified by molecule DOTAP (Figure 1). Because of the structure specialty, Cationic lipid are an amphiphilic entity with a head group having hydrophilicity and lipid tails possessing hydrophobicity.


Figure 1: Structure of DOTAP


Application of Cationic Lipid

The first publication about Cationic lipids to transfect DNA into cells was published by Philip Felgner. Currently, Cationic lipids have become one of few major class of molecules in lipid nanoparticle (LNP) drug delivery vehicles, mRNA vaccine encapsulation. Cationic lipids neutralize negative charges and facilitate encapsulation and cell uptake in lipid nanoparticles (LNP). Usually unsaturated, short (<30 monomer) hydrocarbon chains of the lipids are associated with the highest transduction efficiencies. In aqueous environments, these lipids form micelles with positively charged surfaces that complex with DNA. These lipoplexes act to neutralize charge repulsion between the cell membrane and DNA and promote endocytosis, similar to the mechanism of cationic polymers.

Lipid supplier and customer synthesis

As a leading biochemical supplier worldwide, BroadPharm offer a wide array of Lipid molecules, such as Ionizable lipids, cationic lipids, helper lipids, and PEG lipids to our clients worldwide. BroadPharm also provides fast speed custom synthesis of novel lipid molecules to empower your advanced research.


參考文獻(xiàn)Journal Reference:

1. S. Simoes, A. Filipe, (March 2, 2005). "Cationic liposomes for gene delivery". Expert Opinion on Drug Delivery. 2 (2): 237-254.

2. X. Hou, T. Zaks, R. Langer, Y. Dong, "Nature Review Materials", (2021)

3.B. Pitard, D. Habrant , Supramolecular Medicinal Chemistry and Chemical Biology, in Comprehensive Supramolecular Chemistry II, 2017


靶點科技(北京)有限公司

靶點科技(北京)有限公司

地址:中關(guān)村生命科學(xué)園北清創(chuàng)意園2-4樓2層

© 2025 版權(quán)所有:靶點科技(北京)有限公司  備案號:京ICP備18027329號-2  總訪問量:293724  站點地圖  技術(shù)支持:化工儀器網(wǎng)  管理登陸

亚洲成a人片77777kkkk| 女人被男人吃奶到高潮| 小雪被老汉各种姿势玩弄| 人妻夜夜爽天天爽三区麻豆av网站| 国产精品成人无码免费| 对付老公出轨最狠的一招| free紧videoxx粗又长| 丰满少妇被猛烈进入无码| 客厅玩朋友娇妻hd完整版视频| 人人做人人爽人人爱| 添女人下边视频全过程| 男男情趣玩具play高h| 亚洲熟女少妇一区二区三区| 宝贝把奶露出来h| 久久久久久国产精品免费免费| 久久亚洲精品中文字幕无男同| 欧美精品视频一区二区三区| 成人区精品一区二区婷婷| 国产精品成人99一区无码| 精品亚洲一区二区三区在线观看 | 中国男男自慰gay片免费观看| 人与禽性视频77777| 蜜臀AV无码一区二区三区| 无码人妻av一区二区三区| 久久久久久久精品免费看| 久久久久久亚洲精品无码| 特大黑人与亚洲娇小| 天天操天天干| 人人妻人人澡人人爽| 日韩人妻一区二区三区免费 | 色噜噜狠狠狠综合曰曰曰| 约附近100元3小时微信| 日日噜狠狠噜天天噜AV| 偷拍真实夫妇作爱视频| 东北浓毛老妇国语对白| 99久久国产精品无码| 我的师妹不可能是傻白甜| 少妇高潮灌满白浆毛片免费看| 久久精品夜夜夜夜夜久久| 精品人妻无码专区在中文字幕| 狂野欧美性猛交免费视频|